Neurologists finds potential route to better treatments for Fragile X, autism
When you experience something, neurons in the brain send chemical signals called neurotransmitters across synapses to receptors on other neurons. How well that process unfolds determines how you...
View Article22 million women aged over 50 are affected by osteoporosis in the European Union
A recent report issued by the International Osteoporosis Foundation (IOF) estimates that more than 22 million women aged between 50-84 years in the European Union (EU) have osteoporosis. Postmenopausal...
View ArticleAutomated system could efficiently identify high-risk osteoporosis patients
An automated system that identifies high-risk osteoporosis patients being treated for fractures and can generate letters encouraging follow-up is an effective way to promote osteoporosis intervention...
View ArticleScientists uncover trigger for most common form of intellectual disability...
A new study led by Weill Cornell Medical College scientists shows that the most common genetic form of mental retardation and autism occurs because of a mechanism that shuts off the gene associated...
View ArticleNew test makes Parkinson's-like disorder of middle age detectable in young...
The very earliest signs of a debilitating neurodegenerative disorder, in which physical symptoms are not apparent until the fifth decade of life, are detectable in individuals as young as 30 years old...
View ArticleResearch points to potential treatment strategy for Fragile X syndrome
With no cure available, Fragile X syndrome is the most common form of inherited intellectual disability. Individuals with the syndrome cannot produce enough of a protein—called the fragile X mental...
View ArticleProgressive neurodegenerative disorder linked to R-loop formation
Researchers at UC Davis have identified a new feature of the genetic mutation responsible for the progressive neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS)—the...
View ArticleProteins causing daytime sleepiness tied to bone formation, target for...
Orexin proteins, which are blamed for spontaneous daytime sleepiness, also play a crucial role in bone formation, according to findings by UT Southwestern Medical Center researchers. The findings could...
View ArticleSocialization relative strength in fragile X longitudinal study
Standard scores measuring "adaptive behavior" in boys with fragile X syndrome tend to decline during childhood and adolescence, the largest longitudinal study of the inherited disorder to date has found.
View ArticleA nucleotide change could initiate fragile X syndrome
Researchers reveal how the alteration of a single nucleotide—the basic building block of DNA—could initiate fragile X syndrome, the most common inherited form of intellectual disability. The study...
View ArticleFormer fashion photographer celebrates beauty in human diversity
Award-winning fashion photographer Rick Guidotti crisscrossed the globe taking photos for renowned clients such as Yves Saint Laurent, Revlon and GQ. Now, he uses his eye for beauty to capture images...
View ArticleTests will track improved thinking in people with fragile X, down syndromes
Leading researchers, funded through a new, five-year, $3.2 million grant from the National Institutes of Health (NIH), are collaborating to develop and evaluate tests designed to measure and track...
View ArticleResearch shows spaced training improves long term memory in mice with fragile...
(Medical Xpress)—Research on mice with fragile X syndrome (FXS) suggests that multiple, spaced training sessions can enhance learning and long term memory when longer, continuous sessions do not....
View ArticleMolecule for Fragile X Syndrome treatment receives orphan designation
The European Medicines Agency (EMA) has granted "orphan designation" to BMS 204352, a molecule developed by the CNRS to treat Fragile X Syndrome, a rare genetic disease for which there exists no...
View ArticleNew insights that link Fragile X syndrome and autism spectrum disorders
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability (ID), as well as the most frequent monogenic cause of autism spectrum disorders (ASD). FXS is caused by the...
View ArticleNew toolkit to aid implementation of fracture liaison services
Health authorities worldwide are coping with rising costs and disability resulting from fragility fractures in the older population. Yet evidence shows that the burden of fragility fractures could be...
View ArticleFragile X study offers hope of new autism treatment
People affected by a common inherited form of autism could be helped by a drug that is being tested as a treatment for cancer.
View ArticleNew findings reveal genetic brain disorders converge at the synapse
Several genetic disorders cause intellectual disability and autism. Historically, these genetic brain diseases were viewed as untreatable. However, in recent years neuroscientists have shown in animal...
View ArticleNew genetic clues found in fragile X syndrome
Scientists have gained new insight into fragile X syndrome—the most common cause of inherited intellectual disability—by studying the case of a person without the disorder, but with two of its classic...
View ArticleTime for balance? Preventing atypical femoral fractures related to...
Physicians worldwide frequently prescribe bisphosphonates such as alendronate (Fosamax) and ibandronate (Boniva) to treat osteoporosis and prevent fragility fractures. Unfortunately, long-term...
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